Zaizao Wan (Rebuilding Pill)
【Prescription】20g Qishe Meat (蕲蛇肉), 15g Quanxie (全蝎), 5g Dilong (地龙), 10g Jiangcan (僵蚕, stir-fried), 10g Chuan Shan Jia (穿山甲, processed), 10g Bao Gu (豹骨, processed), 5g Shexiang (麝香), 15g Water Buffalo Horn Powder (水牛角浓缩粉), 2.5g Artificial Niu Huang (人工牛黄), 10g Gui Jia (龟甲, processed), 10g Zhusha (朱砂), 20g Tianma (天麻), 20g Fangfeng (防风), 20g Qianghuo (羌活), 20g Baizhi (白芷), 20g Chuanxiong (川芎), 15g Gegen (葛根), 20g Mahuang (麻黄), 20g Rougui (肉桂), 10g Xixin (细辛), 10g Fuzi (附子, processed), 10g You Song Jie (油松节), 20g Sangjisheng (桑寄生), 10g Gusui Bu (骨碎补, stir-fried), 15g Weilingxian (威灵仙, wine-fried), 20g Fenbixie (粉萆薢), 10g Danggui (当归), 10g Chisha (赤芍), 2.5g Pian Jianghuang (片姜黄), 7.5g Xuejie (血竭), 5g Sanqi (三七), 10g Ruxiang (乳香, processed), 10g Moyi (没药, processed), 20g Renshen (人参), 20g Huangqi (黄芪), 18g Baizhu (白术, stir-fried), 10g Fuling (茯苓), 20g Gancao (甘草), 10g Tianzhuhuang (天竺黄), 20g Zhi Heshouwu (制何首乌), 20g Shudihuang (熟地黄), 20g Xuanshen (玄参), 20g Huanglian (黄连), 20g Dahuang (大黄), 40g Huajuhong (化橘红), 10g Qingpi (青皮, vinegar-fried), 10g Chenxiang (沉香), 5g Danshen (檀香), 20g Guanghuoxiang (广藿香), 10g Mu Dingxiang (母丁香), 2.5g Bingpian (冰片), 10g Wuyao (乌药), 10g Doukou (豆蔻), 20g Caodoukou (草豆蔻), 10g Xiangfu (香附, vinegar-processed), 20g Liangtoudian (两头尖, vinegar-processed), 40g Jianqu (建曲), 5g Hongqu (红曲).
【Formula Analysis】The main ingredients include Renshen (人参), Huangqi (黄芪), Shudihuang (熟地黄), Gui Jia (龟甲), Gusui Bu (骨碎补), Zhi Heshouwu (制何首乌), and Xuanshen (玄参) which nourish Qi and blood, tonify Yin and kidney. Qishe Meat (蕲蛇肉), Quanxie (全蝎), Dilong (地龙), Jiangcan (僵蚕), and Tianma (天麻) are used to calm wind and relieve spasms, serving as the monarch herbs. The minister herbs include Fenbixie (粉萆薢), You Song Jie (油松节), Weilingxian (威灵仙), Sangjisheng (桑寄生), Mahuang (麻黄), Fangfeng (防风), Qianghuo (羌活), Gegen (葛根), Chuan Shan Jia (穿山甲), Bao Gu (豹骨), Baizhi (白芷), Chuanxiong (川芎), Xixin (细辛), Chisha (赤芍), Pian Jianghuang (片姜黄), Fuling (茯苓), Doukou (豆蔻), Caodoukou (草豆蔻), and Liangtoudian (两头尖) which dispel wind and eliminate dampness, unblock channels and relieve pain. Niu Huang (牛黄), Water Buffalo Horn, Zhusha (朱砂), and Tianzhuhuang (天竺黄) are used to dispel wind, transform phlegm, and calm the spirit, serving as the minister herbs. The assistant herbs include Chenxiang (沉香), Xiangfu (香附), Ruxiang (乳香), Moyi (没药), Sanqi (三七), Xuejie (血竭), Danshen (檀香), and Wuyao (乌药) which invigorate blood circulation and disperse stasis; Dahuang (大黄) and Huanglian (黄连) clear heat and dry dampness, invigorate blood and dispel stasis; Huajuhong (化橘红), Baizhu (白术), Gancao (甘草), Jianqu (建曲), Hongqu (红曲), Qingpi (青皮), Guanghuoxiang (广藿香), and Mu Dingxiang (母丁香) regulate Qi and strengthen the spleen; Fuzi (附子) and Rougui (肉桂) warm and tonify Qi and blood to support the foundation and strengthen the source, allowing blood to flow and dispel wind. Bingpian (冰片) and Shexiang (麝香) are aromatic and open the orifices to awaken the mind, guiding the medicine to the affected area. Together, these herbs work to dispel wind, transform phlegm, invigorate blood, and unblock channels.
【Functions and Indications】Dispels wind, transforms phlegm, invigorates blood, and unblocks channels. It is used for stroke caused by wind-phlegm obstructing the channels, with symptoms including facial asymmetry, hemiplegia, numbness of limbs, pain and spasms, and slurred speech.
【Preparation Method】All fifty-eight ingredients, except for Shexiang (麝香), Water Buffalo Horn Powder, Artificial Niu Huang, and Bingpian (冰片), are finely powdered; the remaining fifty-three ingredients including Qishe Meat (蕲蛇肉) are crushed into fine powder. Shexiang (麝香), Water Buffalo Horn Powder, Artificial Niu Huang, and Bingpian (冰片) are finely ground and mixed with the above powders, then sieved and blended. For every 100g of powder, add 120-150g of honey to form large honey pills.
【Dosage Form and Specification】Pill form. Each pill weighs 9g.
【Dosage】Oral administration. 1 pill at a time, 2 times a day.
【Quality Control】
1. The product is a brownish-black large honey pill; it has a fragrant aroma and a slightly sweet, bitter taste.
2. Microscopic identification of Qishe Meat (蕲蛇肉), Quanxie (全蝎), Jiangcan (僵蚕), Chuanxiong (川芎), Gegen (葛根), Mahuang (麻黄), Rougui (肉桂), Danggui (当归), Chisha (赤芍), Baizhi (白术), Gancao (甘草), Fuling (茯苓), Huanglian (黄连), Dahuang (大黄), Doukou (豆蔻), Huangqi (黄芪), Qingpi (青皮), Fangfeng (防风), and Shudihuang (熟地黄).
3. It should comply with all relevant regulations for pills.
【Contraindications】Not for use by pregnant women.
【Modern Research】This product mainly exhibits anticoagulant, improves microcirculation, and anti-inflammatory effects.
【Clinical Applications】Clinically used for stroke, facial asymmetry, hemiplegia, numbness of limbs, pain and spasms, and slurred speech due to wind-phlegm obstructing the channels.
【Formula Song】Fifty-eight ingredients in Zaizao Wan, an ancient secret formula from the Qing Dynasty, specifically treats wind-phlegm for paralysis, with effects as renowned as its name.
【Storage】Seal and store in a cool place.
Xiao Huoluo Wan (Small Activating Pill)
【Prescription】180g Dan Nan Xing (胆南星), 180g Zhi Chuan Wu (制川乌), 180g Zhi Cao Wu (制草乌), 180g Dilong (地龙), 66g Ruxiang (乳香, processed), 66g Moyi (没药, processed).
【Formula Analysis】In this formula, Zhi Chuan Wu (制川乌) and Zhi Cao Wu (制草乌) are pungent and warm, dispelling wind and drying dampness, unblocking channels and relieving pain, serving as the monarch herbs. Dan Nan Xing (胆南星) dispels wind, dries dampness, and clears heat to transform phlegm, serving as the minister herb. Dilong (地龙) is good at moving and unblocking channels; Ruxiang (乳香) and Moyi (没药) invigorate Qi and blood, transform stasis, unblock channels, and relieve pain. Together, these herbs work to dispel wind, scatter cold, transform phlegm, eliminate dampness, invigorate blood, and relieve pain.
【Functions and Indications】Dispels wind, scatters cold, transforms phlegm, eliminates dampness, invigorates blood, and relieves pain. It is used for bi syndrome caused by wind-cold-dampness obstruction and phlegm-stasis obstructing the channels, with symptoms including joint pain in limbs, cold pain, stabbing pain, or pain worsening at night, difficulty in joint flexion and extension, and numbness and spasms.
【Preparation Method】The above six ingredients are finely powdered, sieved, and mixed. For every 100g of powder, add 120-130g of honey to form large honey pills.
【Dosage Form and Specification】Large honey pills, each weighing 3g.
【Dosage】Take with yellow wine or warm water. 1 pill at a time, 2 times a day.
【Quality Control】
1. The product is a blackish-brown to black large honey pill; it has a fishy smell and a bitter taste.
2. Microscopic identification of Dan Nan Xing (胆南星), Zhi Cao Wu (制草乌), and Moyi (没药).
3. Thin-layer chromatography is used for the limit test of alkaloids in Wu Tou.
4. It should comply with all relevant regulations for pills.
【Contraindications】Not for use by those with Yin deficiency and heat, or by pregnant women.
【Modern Research】It mainly exhibits analgesic, anti-inflammatory, and immunosuppressive pharmacological effects. Xiao Huoluo Wan can significantly reduce the number of twisting movements in mice induced by acetic acid, decrease the capillary permeability in acetic acid-induced mouse peritonitis, inhibit the proliferation of granulation tissue caused by cotton balls, and has a good inhibitory effect on joint swelling caused by Freund’s complete adjuvant, significantly reducing blood viscosity at low shear rates and decreasing hematocrit, indicating that Xiao Huoluo Wan has strong anti-inflammatory, analgesic, and blood-invigorating effects.
【Clinical Applications】Clinically used for rheumatoid arthritis, chronic rheumatic arthritis, osteophyte disease, sciatica, and shoulder periarthritis, all of which are due to wind-cold-dampness and phlegm-stasis obstructing the channels.
【Other Preparations】Xiao Huoluo Pian (小活络片) (as per the “Ministry Standard” in the 15th volume of TCM Formulations) for oral use. 4 tablets at a time, 2 times a day.
【Formula Song】Xiao Huoluo Dan, two Wus together, Ruxiang, Moyi, Dan Nan Xing, and Dilong, cold-dampness and stasis cause bi pain, dispel wind and invigorate blood to unblock the channels.
【Storage】Seal and store in a cool place.